Yes, no problem.
I prefer the Platypus Big Zip mouth... either 2 liter or 3 liter. I installed a quick disconnect kit to the feeding tube, above the mouthpiece, so that I don't have to remove the bladder to refill. I just disconnect the mouthpiece, fill the extra collapsible water pouch I carry with water, and then screw on the connector cap which clicks the pouch into the quick disconnect. You just quickly squeeze the water from the pouch to fill the bladder, disconnect when finished, then click in the mouthpiece.
It takes about 40 seconds to do all that, and I don't have to open up the pack, dig out the bladder, fill the bladder, then put it back into place.
There are quick disconnect kits for Camelback bladders, too.
https://www.amazon.com/dp/B002IAMPGM/?tag=casaivar02-20
This video demonstrates the installation and function of the quic disconnect. This shows a water filter installed on the bottle, but the collabsible water pouch works the same way without the filter.